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This result, in view of the much lower prevalence of SH in men, suggests that many of these subjects are euthyroid outliers.

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Meanwhile, clinicians should have a low threshold for obtaining a serum TSH level in women who have vague suggestive symptoms, who are pregnant or anticipating becoming pregnant, or who have a strong family history of autoimmune thyroid disease.

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Specific factors, such as changes in health or diet, new medications for other conditions, or simply switching brands, can also cause changes in thyroid hormone levels that require different doses.

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Restricting the diagnosis and treatment of hypothyroidism to measuring T4 and TSH, and nothing else, is the approach that seems to be used by conventional medicine in the rest of the World.

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Large doses of L-thyroxine are required for treatment.

While there are definitive guidelines for the duration of treatment of CM, patients who experience a relapse should be continued lifelong therapy.

The need to measure free thyroxine levels has diminished in the past 2 decades, but it's still a frequently ordered test and may be an important one for some patient populations, especially pregnant women.

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Such people may be asymptomatic and whether they should be treated is controversial.

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